
Santa Cruz Holidays
Book a Hotel + Flight or Car together to unlock savings
Your Santa Cruz Holiday
With a Santa Cruz holiday package, you can forget about planning hassles and simply focus on experiencing everything this thrilling destination has to offer. The best way to plan your trip to Santa Cruz is to begin with its most popular cities, which include Samaipata, Roboré and Camiri. Expedia is a one-stop shop when it comes to planning your Santa Cruz holiday. From flights and hotels, to activities and more, we're here to help you create a travel experience like no other.
Top destinations in Santa Cruz

Santa Cruz
Santa Cruz Essential Information
Language | Spanish |
|---|---|
Currency | Bolivian bolivianos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Viru Viru Intl. Airport (VVI) |
Top Sights | Amboró National Park, Santa Cruz Zoo and Lomas de Arena Regional Park |
Our pick of the best Santa Cruz Hotel Deals

Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
The price is AU$69 per night from 2 Mar to 3 Mar
AU$69
2 Mar - 3 Mar
9.6/10 Exceptional! (91 reviews)
Great value
Reviewed on 21 Feb 2026

Camino Real Hotel
Av. San Martín y 4to. Anillo Santa Cruz
The price is AU$164 per night from 6 Mar to 7 Mar
AU$164
6 Mar - 7 Mar
9/10 Wonderful! (420 reviews)
Spotless, large and comfortable room was well maintained. Friendly and helpful staff. Delicious breakfast buffet. Location is near excellent shopping and dining options.
Reviewed on 5 Feb 2026

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455 Santa Cruz
The price is AU$184 per night from 17 Mar to 18 Mar
AU$184
17 Mar - 18 Mar
9/10 Wonderful! (363 reviews)
Very nice and cozy
Reviewed on 28 Feb 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Santa Cruz
Cine Center
You can make plans for a show at Cine Center on your trip to Santa Cruz. While in the area, you can find time to visit its shops.
What to do in Santa Cruz

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
AU$120
per adult

Guided visit to the Che Guevara Memorial in Vallegrande
AU$27
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.












