
Santa Cruz Holidays
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Your Santa Cruz Holiday
With a Santa Cruz holiday package, you can forget about planning hassles and simply focus on experiencing everything this thrilling destination has to offer. The best way to plan your trip to Santa Cruz is to begin with its most popular cities, which include Samaipata, Roboré and Camiri. Expedia is a one-stop shop when it comes to planning your Santa Cruz holiday. From flights and hotels, to activities and more, we're here to help you create a travel experience like no other.
Top destinations in Santa Cruz

Santa Cruz

San Javier
Santa Cruz Essential Information
Language | Spanish |
---|---|
Currency | Bolivian bolivianos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Viru Viru Intl. Airport (VVI) |
Top Sights | Amboró National Park, Santa Cruz Zoo and Lomas de Arena Regional Park |
Our pick of the best Santa Cruz Hotel Deals

Ibis Santa Cruz DE LA Sierra
AVENIDA CRISTOBAL DE MENDOZA, Santa Cruz
The price is AU$67 per night from 11 Sept to 12 Sept
AU$67
11 Sept - 12 Sept
9.4/10 Exceptional! (51 reviews)
"The"
Reviewed on 28 Jul. 2025

Marriott Santa Cruz de la Sierra Hotel
4to Anillo Entre Radial 23, At Calle Las Ramblas, Santa Cruz, Santa Cruz
The price is AU$159 per night from 5 Sept to 6 Sept
AU$159
5 Sept - 6 Sept
9/10 Wonderful! (191 reviews)
"all"
Reviewed on 5 Jun. 2025

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ave. San Martin, #455, Santa Cruz
The price is AU$206 per night from 9 Sept to 10 Sept
AU$206
9 Sept - 10 Sept
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Frequently asked questions
Discover the most popular places to visit in Santa Cruz
Cine Center
You can make plans for a show at Cine Center on your trip to Santa Cruz. While in the area, you can find time to visit its shops.
What to do in Santa Cruz

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
AU$130
per adult

3D/2N Getaway on the Che Guevara Route in Bolivia
AU$1,395
per adult
* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.